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| Karapinar,Deniz Yilmaz; Karadas,Nihal; Sivis,Zühal Önder; Yazici,Pinar; Duyu,Muhterem; Metin,Dilek; Karapinar,Bülent; Aydinok,Yeşim. |
| ABSTRACTEmpirical antifungal therapy is most often given to patients with leukemia. However breakthrough fungal infections under antifungal therapy are not uncommon. Four children, with hematologic malignant disease developed mycotic breakthrough infections while on empirical caspofungin treatment for a median of 14 (range 11-19) days. Trichosporon asahii was detected in the blood culture of two patients and Geotrichum capitatum in the other two (one patient also had positive cerebrospinal fluid culture). Because the patients' clinical situation worsened, voriconazole was empirically added for two patients three and five days before the agent was detected. The first sterile blood culture was obtained 3-7 days of voriconazole treatment. All patients reached... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Geotrichum capitatum; Trichosporon asahii; Invazive fungal infection; Febrile neutropenia. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000500549 |
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